Personality research with non-human primates: theoretical formulation and methods

Non-human primates in prion research.

Prion diseases or transmissible spongiform encephalopathies are neurodegenerative disorders affecting a broad range of mammals including humans. Initially thought to be of viral origin, it became apparent that prion diseases are unique transmissible entities where a misfolded, highly stable conformer (PrPSc) of the host encoded prion protein (PrPC) represents an essential component of infectiou...

Experiments with Non-human Primates

J Rehabil Med Suppl 41, 2003 DOI 10.1080/16501960310010124 In this laboratory we have developed a set of techniques that randomized controlled studies indicate can substantially reduce the motor deficit of patients with mild to moderately severe chronic strokes. The techniques, termed Constraint-Induced Movement therapy (CI therapy), involve motor restriction of the less-affected arm while at t...

Experimental Field Studies with Non-human Primates Experimental Field Studies with Non-human Primates

One way to study language evolution is to compare human communication with closely related non-human primate species. This comparative approach has turned to be especially productive if subjects are studied under natural field conditions in which they have evolved. Various observation techniques have been developed, but field experiments are often needed to clarify underlying cause-effect relat...

Alternative methods for the use of non-human primates in biomedical research.

The experimental use of non-human primates (NHP) in Europe is tightly regulated and is only permitted when there are no alternatives available. As a result, NHP are most often used in late, pre-clinical phases of biomedical research. Although the impetus for scientists, politicians and the general public to replace, reduce and refine NHP in biomedical research is strong, the development of 3Rs ...

The welfare of non-human primates used in research